Doses should be taken at least 24 hours apart. The dosage is based on your medical condition, response to treatment, and other medications you may be taking. Be sure to tell your doctor and pharmacist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products).

Vardenafil Warnings/Precautions

The listed SingleCare price references the price of generic drugs if available. Vardenafil and Cialis tend to have similar side effects since they’re both in the same drug class. The most frequently reported side effects include headaches, nasal congestion or a stuffy nose, indigestion, and back pain. In addition, both medications may lead to facial flushing, characterized by redness and warmth in the face. Other common side effects of vardenafil are dizziness, flu symptoms, and inflamed sinuses (sinusitis).

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Other common side effects of Cialis include muscle pain and pain in the arms or legs. Most side effects with these medications are mild and go away on their own. If you experience serious side effects, such as visual changes or sudden hearing loss, seek medical attention immediately. This may not be a complete list of adverse effects that can occur. Please refer to your doctor or healthcare provider to learn more.

Are there reasons why Cialis is a better treatment option than Levitra or vice versa?

PDE5 inhibitors like vardenafil and Cialis work by relaxing and widening blood vessels. This effect can help with the intended benefits of these medications, but it can also lead to some unwanted side effects. Combining vardenafil or Cialis with nitrates, alpha-blockers, or other blood pressure medications (antihypertensives) can lead to a dangerous drop in blood pressure, which may be fatal in severe cases. Vardenafil and Cialis should not be used with guanylate cyclase (GC) stimulators like riociguat for this same reason. Vardenafil and Cialis are both metabolized or processed in the liver. Avoid eating grapefruit fildena online or drinking grapefruit juice while using this medication unless your doctor or pharmacist says you may do so safely.

Property	Description	Value
Molecular Formula	-	C23H32N6O4
Molecular Weight	-	488.54 g/mol
Solubility	In water	Slightly soluble
pKa	-	4.8

Grapefruit can increase the chance of side effects with this medicine.

Product	Dosage	Quantity + Bonus	Price
Cialis Generic	10mg	30 + 4 Pills	63.32€ 60.30€	Buy
Kamagra Oral Jelly	100 mg	21 Sachets	95.92€ 91.35€	Buy
Kamagra Gold	50 mg	120 + 6 Pills	281.13€ 267.74€	Buy
Cialis Generic	10mg	270 + 10 Pills	308.71€ 294.01€	Buy
Priligy Generic Dapoxetine	60mg	180 + 10 Pills	494.76€ 471.20€	Buy
Levitra Professional	20mg	120 + 4 Pills	348.44€ 331.85€	Buy
Cialis Soft Tabs	20mg	30 + 4 Pills	87.43€ 83.27€	Buy
Viagra Generic	150mg	20 Pills	55.02€ 52.40€	Buy
Cialis Soft Tabs	20mg	10 Pills	39.03€ 37.17€	Buy
Levitra Generic	20mg	270 + 10 Pills	376.33€ 358.41€	Buy
Cialis Generic	60mg	30 + 2 Pills	85.33€ 81.27€	Buy
Cialis Generic	60mg	10 Pills	41.22€ 39.26€	Buy
Levitra Soft Tabs	20mg	10 Pills	52.27€ 49.78€	Buy
Viagra Generic	150mg	120 + 8 Pills	177.58€ 169.12€	Buy
Kamagra Gold	100 mg	180 + 6 Pills	436.79€ 415.99€	Buy
Viagra Generic	150mg	270 + 10 Pills	326.61€ 311.06€	Buy

Ask your doctor or pharmacist for more details.

• Vardenafil is sometimes used off-label for pulmonary arterial hypertension.
• Use caution when combining with other vasodilators or certain antidepressants.
• The drug is often prescribed after diagnosis of erectile dysfunction by a clinician.
• It’s essential to follow the prescribed course and not self-medicate.

Tell your doctor if your condition does not get better. Headache, flushing, stuffy/runny nose, or dizziness may occur. Vision changes such as increased sensitivity to light, blurred vision, or trouble telling blue and green colors apart may also occur. If any of these effects last or get worse, tell your doctor or pharmacist promptly.

• 20 mg vardenafil is effective in improving erectile function in most men.
• Be aware of potential allergic reactions, such as rash or swelling.
• The medication can interact with certain antibiotics and antifungals.
• Regular check-ups are recommended during prolonged use of vardenafil.

To reduce the risk of dizziness and lightheadedness, get up slowly when rising from a sitting or lying position.

Publication types

Read the Patient Information Leaflet if available from your pharmacist before you start taking vardenafil and each time you get a refill. If you have any questions, ask your doctor or pharmacist. Take this medication by mouth as directed by your doctor, usually as needed. Take vardenafil, with or without food, about 1 hour before sexual activity. Do not take more than once daily. Remember that this medication has been prescribed because your doctor has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.

What other information should I know?

Trustworthy: All of SingleCare’s content goes through a multi-phase review process by our writers, editors, and Medical Board in order to provide clear and credible information. Vardenafil is used to treat male sexual function problems (impotence or erectile dysfunction-ED). In combination with sexual stimulation, vardenafil works by increasing blood flow to the penis to help a man get and keep an erection. This drug does not protect against sexually transmitted diseases (such as HIV, hepatitis B, gonorrhea, syphilis). Using an effective barrier method (latex or polyurethane condom/dental dams) during sexual activity will help to decrease your risk of infection. Sexual activity may put extra strain on your heart, especially if you have heart problems.

Study	Percentage of Effectiveness	Notes
Clinical Trial A	75%	Improved erectile function
Clinical Trial B	80%	Patient satisfaction rate
Post-Marketing Reports	78%	Overall effectiveness observed

If you have heart problems and experience any of these serious side effects while having sex, stop and get medical help right away: Rarely, sudden decreased vision, including permanent blindness, in one or both eyes (NAION) may occur.

Before Using

These drugs contain different active ingredients and can be used in different ways. Cialis is available as a once-daily pill, while Levitra is only taken as needed. Choosing which is better can depend on personal preferences and how often you plan to be intimate. Cialis may work faster and have effects that last longer than vardenafil. In addition, Cialis may be preferred by those who also have BPH or want a once-daily option.

Pharmacological Class

It’s best to consult a doctor for medical advice about the best option for you. Taking Levitra or Cialis along with alcohol may increase the chances of side effects. Since alcohol affects blood vessels in a way similar to these medications, you might experience more noticeable symptoms, like flushing and dizziness. While small amounts of alcohol might be okay, drinking too much can make these medications less effective. Talk to a doctor about how much alcohol is safe to drink while using these medicines.

Are Levitra and Cialis the same?

There is no single ED drug that is considered the best. ED treatment is highly individualized, and thus, the better choice is the one that helps you the most. Price and potential side effects should also be considered when picking an ED drug with your healthcare provider. Erectile dysfunction prevalence in the United States: report from the 2021 National Survey of Sexual Wellbeing, The Journal of Sexual Medicine (2024) Determination that Levitra (vardenafil hydrochloride) tablets, 2.5 milligrams were not withdrawn from sale for reasons of safety or effectiveness, Federal Register (2019) A comparison of the available phosphodiesterase-5 inhibitors in the treatment of erectile dysfunction: a focus on avanafil, Patient Preference and Adherence (2015) Determining the earliest time within 30 minutes to erectogenic effect after tadalafil 10 and 20 mg: a multicenter, randomized, double-blind, placebo-controlled, at-home study, The Journal of Sexual Medicine (2004) Phosphodiesterase-5 (PDE5) inhibitors in the management of erectile dysfunction, Pharmacy & Therapeutics (2013) PDE-5 inhibitors in scleroderma Raynaud phenomenon and digital ulcers: Current status of clinical trials, International Journal of Rheumatology (2011) Phosphodiesterase 5 inhibitors for pulmonary hypertension, Cochrane Database of Systematic Reviews (2019) Phosphodiesterase-5 inhibitors help climbers to achieve new heights, BJUI Internacional (2006) Comparative effectiveness and safety of oral phosphodiesterase type 5 inhibitors for erectile dysfunction: a systematic review and network meta-analysis, European Urology (2013) The effect of phosphodiesterase-type 5 inhibitors on erectile function: an overview of systematic reviews, Frontiers in Pharmacology (2021) Medically accurate: SingleCare’s Medical Review Board analyzes all of our content to confirm it’s in line with current medical advice. Evidence-based: Our content is sourced from reputable U.S.-based healthcare professionals and peer-reviewed research. If this serious problem occurs, stop taking vardenafil and get medical help right away. You have a slightly greater chance of developing NAION if you have heart disease, diabetes, high cholesterol, certain other eye problems ("crowded disk"), high blood pressure, if you are over 50, or if you smoke.

• 20 mg vardenafil is used to treat erectile dysfunction in men.
• It enhances blood flow to the penis during sexual activity.
• Vardenafil should be taken about 30-60 minutes before sex.
• The usual dose varies; 20 mg is a common prescribed amount.

Rarely, a sudden decrease or loss of hearing, sometimes with ringing in the ears and dizziness, may occur. Stop taking vardenafil and get medical help right away if these effects occur. In the rare event you have a painful or prolonged erection lasting 4 or more hours, stop using this drug and get medical help right away, or permanent problems could occur. Get medical help right away if you have any very serious side effects, including: A very serious allergic reaction to this drug is rare. However, get medical help right away if you notice any symptoms of a serious allergic reaction, including: itching/swelling (especially of the face/tongue/throat) This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.

Tips for Taking Vardenafil and Viagra Effectively

The doses of these drugs may need to be adjusted when taking other drugs that alter certain liver enzymes, such as the CYP3A4 enzyme. Therefore, caution is recommended when mixing vardenafil or Cialis with certain antibiotics, antifungals, and anticonvulsants (seizure medications), among others. In addition, grapefruit juice may increase the levels of vardenafil and Cialis in the body, which may lead to adverse effects. This is not a complete list of drug interactions. Please consult your doctor before taking these medications.

Approved as Treatment by the FDA

Taking a drug like vardenafil or Cialis may increase the risk of heart attack, stroke, or other heart problems in people with heart disease. The use of vardenafil and Cialis should be avoided in people with a history of unstable angina (chest pain), uncontrolled high blood pressure, stroke, heart attack, arrhythmia, and/or severe heart disease. PDE5 inhibitors can increase the risk of dangerously low blood pressure, particularly when combined with other blood pressure medications. It is important to monitor blood pressure regularly if you are prescribed these drugs. If you experience priapism, or a painful erection that lasts longer than 4 hours, seek emergency medical attention.

What should I tell my healthcare provider before taking vardenafil?

Priapism can cause damage to the penile tissue if it’s not treated promptly. Visual problems, such as sudden vision loss, are rare adverse effects of vardenafil and Cialis. Using these medications can also increase the risk of a sudden tadalis 20 decrease or loss of hearing. Seek prompt medical attention if you experience these effects. Levitra and Cialis belong to the same class of drugs called PDE5 inhibitors, but they are not the same drugs. You may report side effects to FDA at 1-800-FDA-1088 or at In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.