When used topically on the skin, it can create numbness and desensitizes the area.
See also
Prescription pills – like SRIs (sertraline, paroxetine) and PDE5 inhibitors (sildenafil, tadalafil, vardenafil) – are often also used to treat PE by adjusting serotonin levels in the brain, which can help prolong intimacy. The best PE treatment depends on your symptoms, preferences and any other health concerns. A licensed provider can help you choose the right option for safe and effective results. Premature ejaculation treatments are available in two main types: topical and oral medications. Topical treatments are applied directly to the genitals to reduce sensation and help delay ejaculation.
Basic questions to ask your doctor
Common options include desensitizing creams or sprays and benzocaine wipes. Oral medications can help men maintain an erection or delay climax. Two main categories used for premature ejaculation are selective serotonin reuptake inhibitors (SSRIs), which are a type of antidepressant, and PDE5 inhibitors, which are typically prescribed for erectile dysfunction. Topical treatments are applied directly to the genitals anywhere from five to 20 minutes before intercourse to reduce sensation and have been shown to delay orgasm in men by three to six minutes.2 However, for some users, topical treatments can cause loss of sexual desire or erectile disruption due to numbness.3 One risk of using topical treatments for PE is that the numbing ingredients can transfer to your partner, reducing sensation for them as well. Using a condom can mitigate the transfer of topical treatment to your partner during sexual contact. Benzocaine wipes4 have been developed specifically for PE as a convenient method to apply anesthetic to the genitals.
| Product | Dosage | Quantity + Bonus | Price | |
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Its ability to help men with PE last longer during intercourse has shown promise in small studies. Benzocaine wipes for PE are available over the counter. The price for benzocaine wipes varies widely – averaging approximately $2 to $6 per wipe.5 Selective serotonin reuptake inhibitors (SSRIs) are medications generally prescribed for mental health conditions like depression and anxiety.
- Topical gels can numb nerves and delay ejaculation temporarily.
- Oral pills like dapoxetine are prescription medications for PE.
- Herbal supplements claim to improve stamina and control.
- SSRIs often prescribed off-label to help delay climax.
- Some lifestyle changes, like stress reduction, may improve symptoms.
One of the side effects of SSRIs is delayed ejaculation and studies6 show this can help with PE symptoms.
| Medication Name | Active Ingredient | Usage Frequency | Typical Dose | Side Effects | Prescription Required | Cost ($) |
|---|---|---|---|---|---|---|
| Dapoxetine | Dapoxetine | As needed | 30 mg before sex | Nausea, dizziness | Yes | 1.5-2.5 |
| SSRIs (off-label) | Sertraline, Paroxetine | Daily | 50-100 mg daily | Fatigue, dry mouth | Yes | 1-2 per pill |
| Tramadol (off-label) | Tramadol | As needed | 50 mg | Drowsiness, nausea | Yes | 0.50-0.80 per pill |
Because of this, medical best erection pills providers often prescribe SSRIs for PE.
Oral Medications Sometimes Used for PE
Behavioral therapy focuses on retraining your body and mind. Start-stop technique (pausing stimulation before climax) Squeeze technique (applying pressure to reduce arousal) SSRIs can increase ejaculation time by 2–8 times baseline in many men Behavioral techniques can significantly improve control over time Combining medication and behavioral therapy often produces the best results So, it's not necessarily pills vs therapy. For many men, it's pills plus therapy. Understanding the cause helps determine the best solution. If PE develops suddenly after years of normal function, it's especially important to rule out medical causes.
2. Practice
Your PE seems linked to stress or performance anxiety In many cases, doctors recommend starting with behavioral strategies and adding medication if needed. Let's be honest — no medication is risk-free. Serious side effects are uncommon but possible. You should talk to a doctor if: You have symptoms like pain, blood in semen, or urinary problems However, underlying conditions (like hormonal disorders or cardiovascular issues linked to erectile dysfunction) can be serious. Always speak to a doctor if something feels off or symptoms are severe. Sertraline (generic Zoloft) is part of the classification of drugs called SSRIs.
Other treatments against premature ejaculation
Lidocaine cream is a topical PE medication that numbs the application area with local anesthetics. When applied to male genitals, desensitization helps prolong an erection and prevent premature ejaculation. Lidocaine is available via a prescription or over the counter. RedBox Rx offers prescription-strength 4% lidocaine cream in a 15 gm tube for $30. Benzocaine is a mild anesthetic that is widely available in over-the-counter pain relief products. It is used for the treatment of a wide range of conditions, including depression, anxiety, OCD, PTSD and PMS.7 Although it’s not known exactly how it works, studies8 have shown that sertraline does work for PE. The retail price for sertraline (without insurance) is around $37 for a one-month supply.9 At Redbox Rx it starts at $25 per month. Paroxetine (generic Paxil) is another SSRI that has shown promising study results for treating PE.10 Although it is difficult to prove, some researchers believe that SSRIs ability to reduce depression and anxiety could be the foundation for treating PE. PE is a condition that can be wholly psychological rather than fully biological. Paroxetine for PE is available by prescription only and can cost upward of $28 per month without insurance coverage. A RedBox Rx paroxetine prescription starts at $25 per month.
- Prescription pills must be taken under medical supervision.
- Natural remedies often include ingredients like ginseng or yohimbine.
- Over-the-counter delay sprays can also help.
- Consistent use of certain medications may reduce PE frequency.
- Psychological counseling can be effective for performance anxiety.
All RedBox Rx PE prescription medication options are FDA-approved, competitively priced, and customized to your health needs by a licensed U.S. medical professional.
Phosphodiesterase type 5 inhibitors (PDE5 inhibitors)
Update on the Pharmacological Management of Premature Ejaculation: Guidelines and Recent Findings. *Journal of Clinical Medicine*, *11*(16), 4690. Efficacy and safety of dapoxetine for the treatment of premature ejaculation: A systematic review and meta-analysis. European Association of Urology Guidelines on Male Sexual Dysfunction: sexual enhancement pills Premature Ejaculation. *European Urology Focus*, *6*(4), 604–610.
On average, how long does a man last?
We would love to help them too. We provide a database of explanations from real doctors on a range of medical topics. Get started by exploring our library of questions and topics you want to learn more about. Purpose and positioning of servicesUbie Doctor's Note is a service for informational purposes. The provision of information by physicians, medical professionals, etc. PDE5 inhibitors are a classification of medications traditionally prescribed for erectile dysfunction. Additionally, research has shown that PDE5 inhibitors can have positive results when prescribed for premature ejaculation.
Selective serotonin uptake inhibitors (SSRIs)
If medical treatment is required, please consult your doctor or medical institution. We strive to provide reliable and accurate information, but we do not guarantee the completeness of the content. If you find any errors in the information, please contact us. Premature ejaculation (PE)1 is the most common type of sexual dysfunction in men. It affects as many as 30% to 40% of all men at some point in their life.
Intromission time
It can have a wide range of causes, from hypersensitivity to medical conditions to psychological factors.The critical thing to remember when treating PE is that you are not alone. The condition is very common, even if it is not openly discussed, and is easily treatable. Premature ejaculation (PE) treatments include prescription pills, numbing creams and desensitizing wipes. Each tadalis 20 works differently to help delay climax. Numbing creams and wipes contain local anesthetics such as lidocaine, which reduce sensation on the skin. The best result for treating premature ejaculation is a combination of a PDE5 inhibitor and an SSRI, according to research.11 Sildenafil (generic Viagra) is a commonly prescribed medication to treat erectile dysfunction.
- Some pills are available online but may lack quality control.
- Use of medication should be part of a comprehensive treatment plan.
- Understanding the cause of PE helps tailor the best pill choice.
- Long-term use requires medical guidance to avoid dependency.
- Combining pills with sexual therapy can boost confidence.
Studies12 have shown that sildenafil also benefits men that experience PE. In addition to helping delay ejaculation during vaginal intercourse, study participants reported an increase in sexual confidence, satisfaction and a decrease in recovery time to achieve a second erection after ejaculation.13 A prescription is required to purchase sildenafil for PE. Retail price for sildenafil can be upward of $45 per dose.14 With RedBox Rx, sildenafil starts as low as $1 per dose.
- Some medications are designed specifically for premature ejaculation.
- Using pills without medical advice risks adverse effects.
- Combining pills with behavioral techniques can yield better results.
- Natural pills often lack scientific evidence for efficacy.
- Regular follow-up with a healthcare provider is crucial.
Tadalafil (generic Cialis) is also commonly prescribed for erectile dysfunction. Tadalafil can help treat PE, especially if symptoms for PE and ED are both present. Studies show that taking tadalafil for PE can help men last longer before finishing.15 A prescription is required to purchase tadalafil for PE – with the cost per tablet (without insurance) averaging around $12 per tablet.16 Tadalafil is available for as low as $1 per dose with RedBox Rx. Vardenafil (generic Levitra) is commonly prescribed for ED and has shown promise as a PE treatment as well. In studies, men improved their lasting time, recovery period, control and satisfaction during sexual activity.17 A prescription is required for vardenafil, and without insurance it can cost more than $50 per tablet.18 Vardenafil starts at $3 per tablet with RedBox Rx. RedBox Rx makes receiving treatment for premature ejaculation easy and affordable. Transparent, affordable, flat rates for PE medications with SSRIs for $25 per month (with purchase of three-month supply). $25 online consultations with a U.S.
Why Choose RedBox Rx
If you're dealing with finishing too fast, here's a clear path forward: Give it several weeks of consistent effort. Ask about on-demand vs daily options If anxiety, stress, or relationship conflict is present, therapy can dramatically improve outcomes. So, can a pill stop you from finishing too fast? Yes — for many men, medication can significantly delay ejaculation. But it's not magic, and it's rarely a complete solution on its own.
Male pelvic floor muscles
When looking at Premature ejaculation pills vs behavioral therapy, the evidence suggests: Most importantly, you are not alone, and this is treatable. And don't assume this is something you just have to "live with." If symptoms are ongoing or affecting your quality of life, speak to a doctor. A professional can help rule out serious conditions, discuss safe treatment options, and tailor a plan that fits your needs. The next step is simply choosing to take action. Pharmacological Treatment Options for Premature Ejaculation: A Systematic Review and Meta-Analysis. licensed medical professional. No office wait times or scheduling issues typical with physical medical practices. Start your PE treatment today with our quick and easy online assessment. There are clinically proven pills that help you delay ejaculation.